Looking to deploy Paint .NET on a network, then you will probably want to generate an MSI in order to distribute it, especially for AD/GPO and ZenWorks environments.
Paint.NET.3.5.10.Install.exe /createmsi CHECKFORUPDATES=0 DESKTOPSHORTCUT=0
The command will generate a 32bit and 64bit MSI. When I ran this command it generated the MSIs in a new folder on the desktop.
There are some additional properties that can be used, but defaults should be fine.
CHECKFORBETAS [off by default]
JPGPNGBMPEDITOR [on by default]
TGAEDITOR [on by default]